470 research outputs found
The Roles of Symbols in Neural-based AI: They are Not What You Think!
We propose that symbols are first and foremost external communication tools
used between intelligent agents that allow knowledge to be transferred in a
more efficient and effective manner than having to experience the world
directly. But, they are also used internally within an agent through a form of
self-communication to help formulate, describe and justify subsymbolic patterns
of neural activity that truly implement thinking. Symbols, and our languages
that make use of them, not only allow us to explain our thinking to others and
ourselves, but also provide beneficial constraints (inductive bias) on learning
about the world. In this paper we present relevant insights from neuroscience
and cognitive science, about how the human brain represents symbols and the
concepts they refer to, and how today's artificial neural networks can do the
same. We then present a novel neuro-symbolic hypothesis and a plausible
architecture for intelligent agents that combines subsymbolic representations
for symbols and concepts for learning and reasoning. Our hypothesis and
associated architecture imply that symbols will remain critical to the future
of intelligent systems NOT because they are the fundamental building blocks of
thought, but because they are characterizations of subsymbolic processes that
constitute thought.Comment: 28 page
Lack of class I H-2 antigens in cells transformed by radiation leukemia virus is associated with methylation and rearrangement of H-2 DNA
Transformation of murine thymocytes by
radiation leukemia virus is associated with reduced expression
of the class I antigens encoded in the major histocompatibility
complex (MHC) and increased methylation and altered restriction
enzyme patterns of MHC DNA. These changes may play
a role in host susceptibility to virus-induced leukemogenesis
and accord with the notion that viral genomes play a regulatory
function when they integrate adjacent to histocompatibiity
genes
The Detection of Ionizing Radiation by Plasma Panel Sensors: Cosmic Muons, Ion Beams and Cancer Therapy
The plasma panel sensor is an ionizing photon and particle radiation detector
derived from PDP technology with high gain and nanosecond response.
Experimental results in detecting cosmic ray muons and beta particles from
radioactive sources are described along with applications including high energy
and nuclear physics, homeland security and cancer therapeuticsComment: Presented at SID Symposium, June 201
Plasma Panel Sensors for Particle and Beam Detection
The plasma panel sensor (PPS) is an inherently digital, high gain, novel
variant of micropattern gas detectors inspired by many operational and
fabrication principles common to plasma display panels (PDPs). The PPS is
comprised of a dense array of small, plasma discharge, gas cells within a
hermetically-sealed glass panel, and is assembled from non-reactive,
intrinsically radiation-hard materials such as glass substrates, metal
electrodes and mostly inert gas mixtures. We are developing the technology to
fabricate these devices with very low mass and small thickness, using gas gaps
of at least a few hundred micrometers. Our tests with these devices demonstrate
a spatial resolution of about 1 mm. We intend to make PPS devices with much
smaller cells and the potential for much finer position resolutions. Our PPS
tests also show response times of several nanoseconds. We report here our
results in detecting betas, cosmic-ray muons, and our first proton beam tests.Comment: 2012 IEEE NS
Development of a plasma panel radiation detector: recent progress and key issues
A radiation detector based on plasma display panel technology, which is the
principal component of plasma television displays is presented. Plasma Panel
Sensor (PPS) technology is a variant of micropattern gas radiation detectors.
The PPS is conceived as an array of sealed plasma discharge gas cells which can
be used for fast response (O(5ns) per pixel), high spatial resolution detection
(pixel pitch can be less than 100 micrometer) of ionizing and minimum ionizing
particles. The PPS is assembled from non-reactive, intrinsically radiation-hard
materials: glass substrates, metal electrodes and inert gas mixtures. We report
on the PPS development program, including simulations and design and the first
laboratory studies which demonstrate the usage of plasma display panels in
measurements of cosmic ray muons, as well as the expansion of experimental
results on the detection of betas from radioactive sources.Comment: presented at IEEE NSS 2011 (Barcelona
Drivers and patterns of iron redox cycling from surface to bedrock in a deep tropical forest soil:a new conceptual model
Iron (Fe) reduction and oxidation are important biogeochemical processes coupled to decomposition, nutrient cycling, and mineral weathering, but factors controlling their rates and spatial distribution with depth are poorly understood in terrestrial soils. In aquatic ecosystems, Fe reduction often occurs below a zone of oxic sediments. We tested an alternative conceptual model for Fe redox cycling in terrestrial soils using a deep humid tropical forest soil profile. We hypothesized that Fe reduction in anaerobic microsites scales with depth variation in labile C and Fe availability, as opposed to bulk oxygen (O2). We measured bulk O2 at multiple depths from 0.1 to 5 m quasi-continuously over 18 months and sampled soils from surface to bedrock (~7 m). Median O2 mixing ratios declined from 19.8 ± 1.2 % at 0.25 m to 16.1 ± 1.0 % at 1 m, but did not consistently decrease below 1 m, challenging a recent model of regolith development. Reduced Fe (Fe(II)) extractable in 0.5 M hydrochloric acid was greatest in 0–0.1 m soil and declined precipitously with depth, and did not correspond with visible gleying in B horizons. We observed similar depth trends in potential Fe reduction under anaerobic conditions. Depth trends in Fe(II) also closely mirrored short-term soil respiration and bulk soil C. Labile C stimulated Fe reduction at 0–0.1 m depth, whereas addition of short-range-ordered Fe oxides had no effect. Cultivable Fe-reducing bacterial abundance was four orders of magnitude greater in surface soil (0–0.1 m) than below 1 m. Although cultivable Fe oxidizing bacteria were typically also more abundant in surface soil, addition of labile C and nitrate stimulated Fe oxidizers in deep soil by two orders of magnitude under anaerobic conditions. This implies that infiltration of nitrate (and possibly C) from shallow soil water could potentially promote biotic Fe oxidation, a critical step in bedrock weathering, 7 m below. Together, these data suggest that C, Fe, and nutrient availability increase microbial Fe reduction and oxidation in surface (vs deeper) soil microsites despite high bulk O2, in contrast to the depth segregation of electron accepting processes often observed in aquatic ecosystems. Furthermore, the greatest capacity for Fe redox cycling can occur in A horizons that do not display gleying or mottling
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